MEDIC’s genome-scale CRISPR screen platform
MEDIC’s platform accurately captures tumor suppressor and oncogene phenotypes. We perform comparative genome wide CRISPR screens in 2D-monolayers and 3D cancer spheroids, which provide novel candidate drivers that are essential for cancer growth in 3D spheroids and in vivo (Nature, 2020).
MEDIC’s platform provides synergistic drug combinations for cancer drug developments
Identification of effective combination therapies is critical to address the emergence of drug-resistant cancers. We provide an effective strategy to find synergistic drug combinations in high-throughput (Nature biotechnology, 2017).